Cloxacillin in treatment of acute osteomyelitis.

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Cloxacillin in treatment of acute osteomyelitis.

It has been said that when treating acute osteomyelitis, in this the era of antibiotic-resistant bacteria, the antibiotic given to the patient when first seen is usually chosen by "inspired" guesswork (Mercer, 1964). If an antibiotic were available to which all commonly encountered pathogens were sensitive then this guesswork would be eliminated. It would be unnecessary to change an antibiotic ...

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Experience in treatment of 348 children with acute hematogenic osteomyelitis is analysed. Newborn infants and children whose ages ranged from 1 to 15 years formed a group of patients. Of decisive importance in the outcome of the disease are early diagnosis and emergency operative measures, aimed at decompressing, opening and cleansing the purulent foci, producing a high concentration of antibio...

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Treatment of septic arthritis and acute osteomyelitis

Acute hematogenous bone and joint infections, septic arthritis, and osteomyelitis with or without adjacent septic arthritis, are rare among children in a standard Western setting, but still potentially devastating diseases, as even deaths have been reported recently. Foir this reason, and in part due to historical reasons, the treatment has comprised of months-long courses of antibiotics, start...

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Long-term follow-up trial of oral rifampin-cotrimoxazole combination versus intravenous cloxacillin in treatment of chronic staphylococcal osteomyelitis.

Oral therapies alternative to fluoroquinolones against staphylococcal chronic osteomyelitis have not been evaluated in comparative studies. Consecutive nonaxial Staphylococcus aureus chronic osteomyelitis cases were included in a comparative trial after debridement. Fifty patients were randomized: group A (n = 22) was treated with cloxacillin for 6 weeks intravenously plus 2 weeks orally (p.o.)...

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Some problems in the diagnosis and treatment of acute osteomyelitis.

Acute osteomyelitis is common and may still cause serious permanent disability even though antibiotic treatment is given. The early diagnosis is often difficult and many problems in treatment remain unanswered. Forty-five patients with acute osteomyelitis were admitted to the orthopaedic department of Fulham Hospital under the care of Mr Lipmann Kessel between December 195 1 and December 1958. ...

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ژورنال

عنوان ژورنال: BMJ

سال: 1967

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.2.5549.414